A 55-year-old male underwent a radical retropubic prostatectomy

A 55-year-old male underwent a radical retropubic prostatectomy in 2006. Pathologic analysis conducted at that time revealed adenocarcinoma of the prostate gland with a Gleason score of 4 + 4, positive surgical margins, and lymph involvement in 4 pelvic nodes. Immediately following surgery, his serum prostate-specific antigen (PSA) level was undetectable.

However, 8 months after surgery, his PSA rose to 0.8 ng/mL and on follow-up 3 months later his PSA was 3 ng/mL. The patient was treated with androgen deprivation therapy (ADT) using the gonadotropin-releasing hormone (GnRH) agonist leuprolide acetate (depot formulation at a dose of 7 mg once a month), and his PSA level became undetectable.

Three years later the patient presented with a PSA of 65 ng/mL and a castrate level of serum testosterone of 23 ng/dL. His PSA-doubling time (PSA-DT) was < 6 months. The patient also complained of lower back and pelvic pain and severe fatigue and had recently experienced a weight loss of about 15 pounds.

Subsequent computed tomography (CT)  and bone scans showed clear evidence of metastatic disease and he was treated with docetaxel 75 mg/m2 every 3 weeks plus prednisone (5 mg twice daily) for 8 cycles. Although he initially experienced some symptomatic relief, only very minor reductions in his tumor volume were observed. The patient was considered unresponsive to docetaxel and subsequent treatment options were discussed.

Discuss Newer Treatment Options for Metastatic Castration-Resistant Prostate Cancer

Calculate the price
Make an order in advance and get the best price
Pages (550 words)
*Price with a welcome 15% discount applied.
Pro tip: If you want to save more money and pay the lowest price, you need to set a more extended deadline.
We know how difficult it is to be a student these days. That's why our prices are one of the most affordable on the market, and there are no hidden fees.

Instead, we offer bonuses, discounts, and free services to make your experience outstanding.
How it works
Receive a 100% original paper that will pass Turnitin from a top essay writing service
step 1
Upload your instructions
Fill out the order form and provide paper details. You can even attach screenshots or add additional instructions later. If something is not clear or missing, the writer will contact you for clarification.
Pro service tips
How to get the most out of your experience with Nursing Papers Writer
One writer throughout the entire course
If you like the writer, you can hire them again. Just copy & paste their ID on the order form ("Preferred Writer's ID" field). This way, your vocabulary will be uniform, and the writer will be aware of your needs.
The same paper from different writers
You can order essay or any other work from two different writers to choose the best one or give another version to a friend. This can be done through the add-on "Same paper from another writer."
Copy of sources used by the writer
Our college essay writers work with ScienceDirect and other databases. They can send you articles or materials used in PDF or through screenshots. Just tick the "Copy of sources" field on the order form.
See why 20k+ students have chosen us as their sole writing assistance provider
Check out the latest reviews and opinions submitted by real customers worldwide and make an informed decision.
Customer reviews in total
Current satisfaction rate
3 pages
Average paper length
Customers referred by a friend
15% OFF your first order
Use a coupon FIRST15 and enjoy expert help with any task at the most affordable price.
Claim my 15% OFF Order in Chat